Except for the Beagles, all the dogs at the Animal Resource Center are acquired through pound seizure:

Pound seizure is the practice of allowing government-run facilities to take lost, stray, or abandoned dogs and cats from taxpayer-funded animal shelters for use in animal experiments.

Pound seizure is illegal in England, Denmark, Sweden, and Holland. In the United States there is no federal law regarding pound seizure, but 14 states forbid it: Maine, New Hampshire, Vermont, Massachusetts, Connecticut, Rhode Island, New York, New Jersey, Delaware, Pennsylvania, Maryland, West Virginia, South Carolina, and Hawaii. Most other states have no law on the matter and leave it up to county or town governments to decide, but five states require pound seizure of government-run facilities. These states are: Iowa, Minnesota, Oklahoma, South Dakota, and Utah. There have been several anti-pound seizure bills before Congress, but none have yet been enacted.

The ARC acquires the dogs from Davis and Utah counties (Salt Lake County does not allow this seizure). They have names. Each and every one of them. And yet most of them will die.

   Cardiac Death - One experiment is being conducted by Robert L. Lux to study cardiac death. “The overall objective of Subproject 4.1, Ventricular Repolarization of Subproject Pacing Induced Canine Model Heart Failure, is to study the distribution rate related changed of repolarization in canine hearts compromised by rapid pacing induced heart failure.”

The Animal Resource Center is put in charge of both acquiring the animals and “disposing” of the animals. Typically, this means killing them, as the experiments typically debilitate the animal so much, death is the only answer. ARC employees don’t want to kill the dogs, though. Just like most people, the animal caretakers have a spot in their heart for your typical domestic animals: dogs and cats. Because of this, they have an adoption program, which puts up for adoption all the dogs still alive after the experiments. This usually equals 20%. This is an in-house program, and is not publicized. Nonetheless, these animals hopefully end up in good homes. The only light in their darkness.

"There is no comprehensive animal model for humankind... The truth is, and always has been, that the first clinical use of new medication in human patients provides the first reliable clues as to what can be expected of it. Pre-marketing research on animals is a lottery; post marketing surveillance comes too late for the first human victims of side-effects."

Dr Peter Mansfield, (GP, Founder-President of 'Doctors in Britain against Animal Experiments'.) Animal Experiments in Medicine: The Case Against,' May 1990